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Review Article | OPEN ACCESS

Nanotechnology and Drug Delivery Part 2: Nanostructures for Drug Delivery

Nelson A Ochekpe1 , Patrick O Olorunfemi2, Ndidi C Ngwuluka2

1Department of Pharmaceutical Chemistry; 2Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, University of Jos, PMB 2084, Jos, Nigeria.

For correspondence:-  Nelson Ochekpe   Email: ochekpen@yahoo.com   Tel:+23408037006372

Received: 4 Nov 2008        Accepted: 13 Jan 2009        Published: 23 June 2009

Citation: Ochekpe NA, Olorunfemi PO, Ngwuluka NC. Nanotechnology and Drug Delivery Part 2: Nanostructures for Drug Delivery. Trop J Pharm Res 2009; 8(3):275-287 doi: 10.4314/tjpr.v8i3.12

© 2009 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..

Abstract

This is the second part of a review on nanotechnology in general and particularly as it pertains to drug deliver. In the earlier paper (Part 1), nanotechnology in nature, its history as well as design and methods were discussed. Its applications, benefits and risks were also outlined. In this paper (Part 2), various nanostructures employed in drug delivery, their methods of fabrication and challenges of nano drug delivery are reviewed. Nanotechnology is one approach to overcome challenges of conventional drug delivery systems based on the development and fabrication of nanostructures. Some challenges associated with the technology as it relates to drug effectiveness, toxicity, stability, pharmacokinetics and drug regulatory control are discussed in this review. Clearly, nanotechnology is a welcome development that is set to transform drug delivery and drug supply chain management, if optimally developed.

Keywords: Nanotechnology, Nanobiotechnology, Drug delivery, Nanostructures, Nanomaterials, Nanocarriers

Impact Factor
Thompson Reuters (ISI): 0.523 (2021)
H-5 index (Google Scholar): 39 (2021)

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